منابع مشابه
from stem cells to germ cells and from germ cells to stem cells
germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...
متن کاملMesenchymal Stem Cells: Signaling Pathways in Transdifferentiation Into Retinal Progenitor Cells
Several signaling pathways and transcription factors control the cell fate in its in vitro development and differentiation. The orchestrated use of these factors results in cell specification. In coculture methods, many of these factors secrete from host cells but control the process. Today, transcription factors required for retinal progenitor cells are well known, but the generation of these ...
متن کاملDifferntiation of Mesenchymal Stem Cells From Cord Blood to Osteblastic Cells
Purpose: This study was carried out to isolate mesenchymal stem cells from full-term cord blood and to differentiate these cells into osteoblastic cells. Materials and Methods: It this study, mesenchymal stem cells were isolated from cord blood and expanded by being cultured in the flask several times. First, the cord blood monoeuc1earcells were separated by ficoll - Hypac before they were cul...
متن کاملBlastema from rabbit ear contains progenitor cells comparable to marrow derived mesenchymal stem cells
Rabbits have the capacity to regenerate holes in their ears by forming a blastema, a tissue that is made up of a group of undifferentiated cells. The purpose of the present study was to isolate and characterize blastema progenitor cells and compare them with marrow mesenchymal stem cells (MSCs). Five New Zealand white male rabbits were used in the present study. A 2-mm hole was created in the a...
متن کاملSignaling pathways involved in chronic myeloid leukemia pathogenesis: the importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells
Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to important signaling pathways such as Hedgehog and Notch that are essential ...
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ژورنال
عنوان ژورنال: Science
سال: 2005
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.310.5745.65